商品介绍

Product Introduction

Bioactivity

名称	Methylene Blue trihydrate
描述	Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate is used as a bacteriologic stain and as an indicator. It inhibits soluble guanylyl cyclase and has been used to treat cyanide poisoning and to lower levels of methemoglobin. It also inhibits tau filament formation (IC50: 1.9μM).
细胞实验	使用方法一、细胞和组织染色 1. 将methylene blue 溶解在适当的溶剂(如水或缓冲液）中,制备一定浓度的染料溶液。 2.将细胞或组织切片浸泡在染料溶液中,通常染色时间为几分钟。 3.清洗后,在显微镜下观察细胞结构或目标分子的分布。二、作为MAO-A抑制剂和抗抑郁、抗焦虑药方法：通过动物模型或细胞培养系统,研究其对神经递质的调节作用。三、神经退行性疾病研究方法：通过动物模型和细胞模型中,研究其神经保护作用。
存储条件	store at low temperature,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度	DMSO : 3.67 mg/mL (9.82 mM), Sonication is recommended.
关键字	vasopressor \| Tau aggregation \| sGC \| Parasite \| NOSynthase \| NOS \| NO Synthase \| Nitric oxide synthases \| MonoamineOxidase \| Monoamine Oxidase \| MicrotubuleAssociated \| Microtubule Associated \| Methylthionine Chloride \| Methylene Blue trihydrate \| Methylene Blue Trihydrate \| methemoglobinemias \| MAO-A \| MAO \| Inhibitor \| inhibit \| Guanylatecyclase \| Guanylate cyclase \| Guanylate Cyclase \| dye \| cGMP \| C.I. Basic Blue 9 \| anxiolytic \| antinociception \| antimalarial \| antidepressant
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