| 名称 | VHL Ligand 8 |
| 描述 | VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. It efficiently facilitates the degradation of AR protein in AR-positive prostate cancer cell lines LNCaP, VCaP, and 22Rv1, exhibiting DC50 values ranging from 0.2-1 nM [1]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 关键字 | VHL Ligand 8 | VHL |
| 相关产品 | Lenalidomide | PT-179 | Pomalidomide | (S,R,S)-AHPC | (S)-Thalidomide | Lenalidomide-Br | Thalidomide | Thalidomide 5-fluoride | Thalidomide-O-COOH | (S,R,S)-AHPC hydrochloride | Thalidomide-5-OH | 5-Aminothalidomide |
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