| 名称 | NH-bis(PEG2-propargyl) |
| 描述 | NH-bis(PEG2-propargyl) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
| 体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 关键字 | PEGs | NH-bis(PEG2-propargyl) | NH-bis(PEG-2-propargyl) | NHbis(PEG2propargyl) | NH bis(PEG2 propargyl) |
| 相关产品 | 6-Maleimidocapronic acid | Decaethylene glycol | 11-Aminoundecanoic acid | Pentaethylene glycol | Azido-PEG1 | N-(4-Carboxycyclohexylmethyl)maleimide | Boc-C16-COOH | Triethylene glycol | Tetraethylene glycol | Bis-Tos-PEG4 | 1,3-Dibromo-5,5-dimethylhydantoin | m-PEG12-NHS ester |
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