| 名称 | Tos-PEG4-t-butyl ester |
| 描述 | Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition. This compound plays a crucial role in the synthesis of a range of PROTACs, including BI-3663, a highly selective PTK2/FAK PROTAC. It employs cereblon ligands to target E3 ligases for the degradation of PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 关键字 | Tos-PEG4-t-butyl ester | Tos-PEG-4-t-butyl ester | TosPEG4tbutyl ester | Tos PEG4 t butyl ester | PEGs |
| 相关产品 | 6-Maleimidocapronic acid | Decaethylene glycol | 11-Aminoundecanoic acid | Pentaethylene glycol | Azido-PEG1 | N-(4-Carboxycyclohexylmethyl)maleimide | Boc-C16-COOH | Triethylene glycol | Tetraethylene glycol | Bis-Tos-PEG4 | 1,3-Dibromo-5,5-dimethylhydantoin | m-PEG12-NHS ester |
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