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化合物m-PEG12-OH
m-PEG12-OH
T18143-25mg
2050595-03-2
TargetMol
560.67
C25H52O13
¥99.00
98.40%
25mg
无质量问题不做退换货处理,下单前请仔细确认,感谢配合!

商品介绍

Product Introduction

Bioactivity

名称m-PEG12-OH
描述m-PEG12-OH (Dodecaethylene Glycol Monomethyl Ether) is a PEG-based PROTAC linker. m-PEG12-OH can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
体外活性PROTACs通过连接器连接两种不同的配体;一个是E3泛素连接酶的配体,另一个是目标蛋白的配体。PROTACs利用细胞内的泛素-蛋白酶体系统,选择性地降解目标蛋白[1]。
存储条件Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
关键字PROTACLinker | PROTAC Linkers | PROTAC Linker | PROTAC | PEGs | PEG | non-cleavable | Non-cleavable | m-PEG12-OH | m-PEG-12-OH | mPEG12OH | m PEG12 OH | linker | Inhibitor | inhibit | Antibody-drug conjugates linkers | ADCLinker | ADC Linkers | ADC Linker | ADC
相关产品6-Maleimidocapronic acid | Decaethylene glycol | 11-Aminoundecanoic acid | Pentaethylene glycol | N-Hydroxysulfosuccinimide sodium | Azido-PEG1 | N-(4-Carboxycyclohexylmethyl)maleimide | Boc-C16-COOH | Succinic anhydride | Bis-Tos-PEG4 | 1,3-Dibromo-5,5-dimethylhydantoin | m-PEG12-NHS ester

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