| 名称 | PC Mal-NHS carbonate ester |
| 描述 | PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound plays a crucial role in facilitating the conjugation of drugs to antibodies, enabling targeted delivery and enhanced efficacy of therapeutic agents. Its unique carbonate ester structure allows for efficient cleavage in the targeted environment, ensuring the controlled release of the drug payload. Its application in ADC synthesis highlights its importance in the development of innovative and targeted cancer therapies. |
| 体外活性 | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| 关键字 | PC Mal-NHS carbonate ester | PC MalNHS carbonate ester | PC Mal NHS carbonate ester | Cleavable | ADCLinker | ADC Linker |
| 相关产品 | DSS Crosslinker | Fmoc-Gly-Gly-OH | Fmoc-8-amino-3,6-dioxaoctanoic acid | Boc-Val-Cit-OH | DSP Crosslinker | Succinic anhydride | EMCS | DSG Crosslinker | SMCC | Boc-NH-PEG4-CH2COOH | N-Boc-PEG5-bromide | MC-Val-Cit-PABC-PNP |
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