| 名称 | N-Acetylgalactosaminyltransferase 1 |
| 描述 | N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer enhances the aberrant O-glycosylation of CD44, activating the Wnt/β-catenin signaling pathway and influencing the malignant behavior of gastric cancer cells. This enzyme plays a crucial role in cancer progression and metastasis by modifying the O-glycosylation of various glycoproteins such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| 相关产品 | Chitosan oligosaccharide | Glycerol | Levulinic acid | Emtricitabine | D-(+)-Trehalose dihydrate | Sucrose | Ferulic Acid | 3-Indoleacetic acid | Gluconate Calcium | D-Pantothenic acid | Thymidine | D(+)-Raffinose pentahydrate |
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